By
Fight Aging Site Team
The good news is that
there are ‘good fats’. Most dietary fats consist of
Triglycerides (TGs) and lesser amounts of Cholesterol. A triglyceride
has 3 fatty acid chains attached to glycerol. Fatty acids are classified
as saturated, mono unsaturated or poly unsaturated fatty acids based
on double bonds between carbons in the chain
Saturated Fatty Acids
have no double bond, are mainly of animal origin, have higher melting
point and are solid at room temperature. Mono unsaturated fatty
acids have one double bond, are found in liquid oils from plants.
Poly unsaturated fatty acids (PUFA) are also found in liquid oils
of plant origin and are the best for cardio vascular health.
Essential Fatty Acids
cannot be made by the body and have to obtained from dietary sources.
They are mainly the Omega 3 fatty acids and Omega 6 fatty acids.
The ideal ratio of Omega 3 to Omega 6 should be around 1:5-10 but
modern day diets are very low in Omega 3 fatty acids. The actual
ratio is anywhere between 1:20 and 1:50, thereby leading to many
chronic disorders.
We shall focus on
the Omega 3 fatty acids, called ‘good fats’ due to their
profound effects on health. The three main Omega 3 fatty acids are
Alpha Linolenic Acid (ALA), Eicosapentaenoic Acid (EPA) and Docosahexaenoic
Acid (DHA).
“The n-3 fatty
acid recommendation to achieve nutritional adequacy, defined as
the amount necessary to prevent deficiency symptoms, is 0.6-1.2%
of energy for ALA; up to 10% of this can be provided by EPA or DHA.”
[1]
“To achieve
recommended ALA intakes, food sources including flaxseed and flaxseed
oil, walnuts and walnut oil, and canola oil are recommended. The
evidence base supports a dietary recommendation of approximately
500 mg/d of EPA and DHA for cardiovascular disease risk reduction.
For treatment of existing cardiovascular disease, 1 g /d is recommended.
These recommendations have been embraced by many health agencies
worldwide.” [1]
Omega 3 fatty acids
are Cardioprotective
“Because of the remarkable cardioprotective effects of omega-3
fatty acids, consumption of food sources that provide omega-3 fatty
acids--especially the longer-chain fatty acids (>or=20 carbons)
from marine sources--should be increased in the diet to decrease
CVD risk significantly.”[2]
“Presently, the weight of the evidence favors recommendations
for modest dietary consumption of ALA (2 to 3 g per day) for the
primary and secondary prevention of CHD.” [3]
Omega 3 fatty acids
improve Insulin Sensitivity
There is overwhelming evidence that switching over to a diet rich
in poly unsaturated fats and mono unsaturated fats, improves insulin
sensitivity significantly. Therefore the progression to ‘metabolic
syndrome’ and Type 2 Diabetes will be significantly curtailed.
[4, 5]
Omega 3 fatty acids may reduce defects of insulin receptor signaling
and thus improve insulin action by other mechanisms. [6]
Omega 3 fatty acids reduce muscle degradation
Insulin increased glucose and amino acid transport; the increase
in glucose transport by insulin was significantly greater after
consumption of the high omega-3 fatty acid diet. High Omega 3 fatty
acid diets reduce net muscle protein degradation altering the composition
of cell membranes and metabolism of muscle protein. [7] This has important
implications for preventing age related muscle loss.
Omega 3 fatty acids
reduce Inflammatory Mediators
Flaxseed oil contains the 18-carbon omega-3 fatty acid alpha-linolenic
acid, which can be converted after ingestion to the 20-carbon n-3
fatty acid eicosapentaenoic acid (EPA). Fish oils contain both 20-
and 22-carbon omega-3 fatty acids, EPA and docosahexaenoic acid.
EPA can act as a competitive inhibitor of arachidonic acid (AA)
conversion to PGE(2) and LTB(4), and decreased synthesis of one
or both of these eicosanoids has been observed after inclusion of
flaxseed oil or fish oil in the diet 8 . It is now well established
that many chronic diseases like atherosclerosis, rheumatoid arthritis,
inflammatory bowel disease, psoriasis and even obesity involve inflammation.
Omega 3 fatty acids
are required for a healthy brain as well. They are needed to produce
hormones, cytokines and neurotransmitters. A deficiency of Omega
3 fatty acids is known to accelerate degenerative changes in the
brain. Docosahexaenoic acid (DHA) is an important structural component
of the brain and nerves. (The subject of another article).
Inclusion of Omega
3 fatty acids in our diet is very important to ‘Fight Aging
and Stay Young’.
References:
1. Gebauer SK et al, Am J Clin Nutr. June 2006; 83(6 Suppl):1526S-1535S
2. Psota TL et al, Am J Cardiol. Aug 2006; 98(4A):3i-18i
3. Mozaffarian D, Altern Ther Health Med. 2005; 11(3):24-30; quiz
31, 79
4. Rivellesse AA et al, Ann N Y Acad Sci. 2002; 967:329-35
5. Ebbesson SO et al, Int J Circumpolar Health. 2005; 64(4):396-408
6. Taouis M et al, Am J Physiol Endocrinol Metab. 2002; 282(3):E664-71
7. Clandinin MT et al, Ann N Y Acad Sci. 1993; 683:151-63
8. James MJ et al Am J Clin Nutr. 2000; 71(1 Suppl):343S-8S
Fight Aging Site team
has taken maximum care to ensure that the information is authentic.
The information has been extracted from published medical trials
and text books. The information is not meant to substitute a Physicians
advice, nor is it meant to treat any disease. Members are advised
to consult a Physician, Dietician, Physiotherapist or Trainer before
taking medication or commencing an exercise program.
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